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Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B.
Menne, Stephan; Tumas, Daniel B; Liu, Katherine H; Thampi, Linta; AlDeghaither, Dalal; Baldwin, Betty H; Bellezza, Christine A; Cote, Paul J; Zheng, Jim; Halcomb, Randall; Fosdick, Abigail; Fletcher, Simon P; Daffis, Stephane; Li, Li; Yue, Peng; Wolfgang, Grushenka H I; Tennant, Bud C.
Afiliación
  • Menne S; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC 20057, United States. Electronic address: sm923@georgetown.edu.
  • Tumas DB; Department of Biology, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Liu KH; Department of Clinical Sciences, Gastrointestinal Unit, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States.
  • Thampi L; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC 20057, United States.
  • AlDeghaither D; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC 20057, United States.
  • Baldwin BH; Department of Clinical Sciences, Gastrointestinal Unit, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States.
  • Bellezza CA; Department of Clinical Sciences, Gastrointestinal Unit, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States.
  • Cote PJ; Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC 20057, United States.
  • Zheng J; Department of Drug Metabolism, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Halcomb R; Department of Chemistry, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Fosdick A; Department of Drug Safety Evaluation, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Fletcher SP; Department of Biology, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Daffis S; Department of Biology, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Li L; Department of Biomarkers, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Yue P; Department of Biomarkers, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Wolfgang GH; Department of Drug Safety Evaluation, Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94404, United States.
  • Tennant BC; Department of Clinical Sciences, Gastrointestinal Unit, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States.
J Hepatol ; 62(6): 1237-45, 2015 Jun.
Article en En | MEDLINE | ID: mdl-25559326
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Pteridinas / Virus de la Hepatitis B de la Marmota / Receptor Toll-Like 7 / Hepatitis B Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Pteridinas / Virus de la Hepatitis B de la Marmota / Receptor Toll-Like 7 / Hepatitis B Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2015 Tipo del documento: Article