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A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.
Sharma, Amitabh; Menche, Jörg; Huang, C Chris; Ort, Tatiana; Zhou, Xiaobo; Kitsak, Maksim; Sahni, Nidhi; Thibault, Derek; Voung, Linh; Guo, Feng; Ghiassian, Susan Dina; Gulbahce, Natali; Baribaud, Frédéric; Tocker, Joel; Dobrin, Radu; Barnathan, Elliot; Liu, Hao; Panettieri, Reynold A; Tantisira, Kelan G; Qiu, Weiliang; Raby, Benjamin A; Silverman, Edwin K; Vidal, Marc; Weiss, Scott T; Barabási, Albert-László.
Afiliación
  • Sharma A; Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Channing Division of Network Medicine, Department of Medicine, Br
  • Menche J; Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Theoretical Physics, Budapest University of Technol
  • Huang CC; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Ort T; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Zhou X; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Kitsak M; Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Sahni N; Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Thibault D; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Voung L; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Guo F; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Ghiassian SD; Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Gulbahce N; Department of Cellular and Molecular Pharmacology, University of California 1700, 4th Street, Byers Hall 308D, San Francisco, CA 94158, USA.
  • Baribaud F; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Tocker J; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Dobrin R; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Barnathan E; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Liu H; Janssen Research & Development, Inc., 1400 McKean Road, Spring House, PA 19477, USA.
  • Panettieri RA; Pulmonary Allergy and Critical Care Division, Department of Medicine, University of Pennsylvania, 125 South 31st Street, TRL Suite 1200, Philadelphia, PA 19104, USA.
  • Tantisira KG; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Qiu W; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Raby BA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Vidal M; Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
  • Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Barabási AL; Center for Complex Networks Research, Department of Physics, Northeastern University, Boston, MA 02115, USA Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Channing Division of Network Medicine, Department of Medicine, Br
Hum Mol Genet ; 24(11): 3005-20, 2015 Jun 01.
Article en En | MEDLINE | ID: mdl-25586491
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Antiasmáticos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article País de afiliación: Brasil
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / Antiasmáticos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article País de afiliación: Brasil