Ultrasonic mediated synthesis of monodispersed lanthanum hydroxide nanorods for possible bioimplant application.
J Mater Sci Mater Med
; 26(1): 5378, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25601669
ABSTRACT
Monodispersed lanthanum hydroxide nano-rods (LaNRs) were synthesized for prospective biomedical application using a microwave heating and ultrasonic agitation methodology which does not require any toxic stabilizing agent. The average length and diameter of the LaNRs thus obtained were 183.4 ± 3.6 and 9.9 ± 0.2 nm respectively, as analyzed by HRTEM. FTIR spectrum confirmed the presence of OH groups. The thermal transformation of lanthanum hydroxide (La(OH)3) was studied by thermogravimetric analysis. The synthesized LaNRs were found to be stable for a period of 1 month at room temperature. They were biocompatible as evaluated by haemocompatibility assay and viability assay using human peripheral blood mononuclear cells. The pro-angiogenic property of LaNRs was demonstrated by in vivo chick chorioallantoic membrane assay. The LaNRs induced osteoblast differentiation of human adipose derived stem cells with significant calcium (Ca(2+)) deposition indicating potential applications in bone tissue engineering.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Materiales Biocompatibles
/
Nanotubos
/
Lantano
Tipo de estudio:
Observational_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Mater Sci Mater Med
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
India