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Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.
Betz, Regina C; Petukhova, Lynn; Ripke, Stephan; Huang, Hailiang; Menelaou, Androniki; Redler, Silke; Becker, Tim; Heilmann, Stefanie; Yamany, Tarek; Duvic, Madeliene; Hordinsky, Maria; Norris, David; Price, Vera H; Mackay-Wiggan, Julian; de Jong, Annemieke; DeStefano, Gina M; Moebus, Susanne; Böhm, Markus; Blume-Peytavi, Ulrike; Wolff, Hans; Lutz, Gerhard; Kruse, Roland; Bian, Li; Amos, Christopher I; Lee, Annette; Gregersen, Peter K; Blaumeiser, Bettina; Altshuler, David; Clynes, Raphael; de Bakker, Paul I W; Nöthen, Markus M; Daly, Mark J; Christiano, Angela M.
Afiliación
  • Betz RC; Institute of Human Genetics, University of Bonn, Bonn, Germany.
  • Petukhova L; Department of Dermatology, Columbia University, NY, NY.
  • Ripke S; Department of Epidemiology, Columbia University, NY, NY.
  • Huang H; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
  • Menelaou A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA.
  • Redler S; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
  • Becker T; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA.
  • Heilmann S; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Yamany T; Institute of Human Genetics, University of Bonn, Bonn, Germany.
  • Duvic M; German Center for Neurodegenerative Diseases, Bonn, Germany.
  • Hordinsky M; Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn.
  • Norris D; Institute of Human Genetics, University of Bonn, Bonn, Germany.
  • Price VH; Department of Genomics, Life&Brain Center, University Bonn, Bonn, Germany.
  • Mackay-Wiggan J; Department of Dermatology, Columbia University, NY, NY.
  • de Jong A; Department of Dermatology, MD Anderson Cancer Center, Houston,TX.
  • DeStefano GM; Department of Dermatology, University of Minnesota, Minneapolis, MN.
  • Moebus S; Department of Dermatology, University of Colorado, Denver, CO, US.
  • Böhm M; Department of Dermatology, University of California, San Francisco, San Francisco CA.
  • Blume-Peytavi U; Department of Dermatology, Columbia University, NY, NY.
  • Wolff H; Department of Dermatology, Columbia University, NY, NY.
  • Lutz G; Department of Genetics & Development, Columbia University, NY, NY.
  • Kruse R; Institute of Medical Informatics, Biometry, and Epidemiology, University Duisburg-Essen, Essen, Germany.
  • Bian L; Department of Dermatology, University of Münster, Münster, Germany.
  • Amos CI; Clinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Lee A; Department of Dermatology, University of Munich, Munich, Germany.
  • Gregersen PK; Dermatological Practice, Hair and Nail, Wesseling, Germany.
  • Blaumeiser B; Dermatological Practice, Paderborn, Germany.
  • Altshuler D; Department of Dermatology, Columbia University, NY, NY.
  • Clynes R; Community and Family Medicine and Genetics, Dartmouth College, Hanover, NH, US.
  • de Bakker PIW; The Feinstein Institute for Medical Research, Manhasset NY.
  • Nöthen MM; The Feinstein Institute for Medical Research, Manhasset NY.
  • Daly MJ; Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
  • Christiano AM; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Nat Commun ; 6: 5966, 2015 Jan 22.
Article en En | MEDLINE | ID: mdl-25608926

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas / Proteínas Proto-Oncogénicas / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple / Proteínas Reguladoras de la Apoptosis / Alopecia Areata / Ataxina-2 / Antígenos HLA / Proteínas de la Membrana Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas / Proteínas Proto-Oncogénicas / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple / Proteínas Reguladoras de la Apoptosis / Alopecia Areata / Ataxina-2 / Antígenos HLA / Proteínas de la Membrana Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido