Occupational asthma from tafenoquine in the pharmaceutical industry: implications for QSAR.
Occup Med (Lond)
; 65(3): 256-8, 2015 Apr.
Article
en En
| MEDLINE
| ID: mdl-25663384
ABSTRACT
We report occupational asthma and rhinitis in a formulation pharmacist, employed in the development of tafenoquine. Tafenoquine is a new anti-malarial drug in development; the pure drug substance has an asthma hazard index of zero and previously was not known to be a respiratory sensitizing agent. The implications of this finding for the refinement of quantitative structural analysis of asthmagenic chemicals are discussed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Relación Estructura-Actividad Cuantitativa
/
Industria Farmacéutica
/
Asma Ocupacional
/
Aminoquinolinas
/
Antimaláricos
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Occup Med (Lond)
Asunto de la revista:
MEDICINA OCUPACIONAL
Año:
2015
Tipo del documento:
Article