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Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies.
Lachmann, Nico; Ackermann, Mania; Frenzel, Eileen; Liebhaber, Steffi; Brennig, Sebastian; Happle, Christine; Hoffmann, Dirk; Klimenkova, Olga; Lüttge, Doreen; Buchegger, Theresa; Kühnel, Mark Philipp; Schambach, Axel; Janciauskiene, Sabina; Figueiredo, Constanca; Hansen, Gesine; Skokowa, Julia; Moritz, Thomas.
Afiliación
  • Lachmann N; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Ackermann M; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Frenzel E; Department of Respiratory Medicine, Hannover Medical School, Hannover 30625, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover 30625, Germany.
  • Liebhaber S; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Brennig S; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Happle C; Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover 30625, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover 30625, Germany.
  • Hoffmann D; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Klimenkova O; Department of Molecular Hematopoiesis, Hannover Medical School, Hannover 30625, Germany.
  • Lüttge D; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Buchegger T; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany.
  • Kühnel MP; Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover 30625, Germany.
  • Schambach A; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Janciauskiene S; Department of Respiratory Medicine, Hannover Medical School, Hannover 30625, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover 30625, Germany.
  • Figueiredo C; Institute for Transfusion Medicine, Hannover Medical School, Hannover 30625, Germany.
  • Hansen G; Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover 30625, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover 30625, Germany.
  • Skokowa J; Department of Molecular Hematopoiesis, Hannover Medical School, Hannover 30625, Germany.
  • Moritz T; RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover 30625, Germany; Institute of Experimental Hematology, Hannover Medical School, Hannover 30625, Germany. Electronic address: moritz.thomas@mh-hannover.de.
Stem Cell Reports ; 4(2): 282-96, 2015 Feb 10.
Article en En | MEDLINE | ID: mdl-25680479
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diferenciación Celular / Técnicas de Cultivo de Célula / Células Madre Pluripotentes Inducidas / Granulocitos / Macrófagos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Stem Cell Reports Año: 2015 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diferenciación Celular / Técnicas de Cultivo de Célula / Células Madre Pluripotentes Inducidas / Granulocitos / Macrófagos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Stem Cell Reports Año: 2015 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos