Biocatalysts for the formation of three- to six-membered carbo- and heterocycles.
Biotechnol Adv
; 33(5): 457-80, 2015.
Article
en En
| MEDLINE
| ID: mdl-25687278
ABSTRACT
During the last decade, the number of different types of enzymes applicable for organic synthesis as biocatalysts has significantly increased. Consequently, the spectrum of reactions has significantly expanded also for cyclisations. This review highlights heterologously expressable biocatalysts transforming non-natural substrates for the formation of three- to six-membered carbo- and heterocycles, excluding terpene cyclases as well as SAM-dependent enzymes. The review focuses on the non-natural substrate scope and the mechanism of the selected enzymes.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Biotecnología
/
Compuestos Heterocíclicos
Idioma:
En
Revista:
Biotechnol Adv
Año:
2015
Tipo del documento:
Article
País de afiliación:
Austria