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Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study.
Costas, L; Infante-Rivard, C; Zock, J-P; Van Tongeren, M; Boffetta, P; Cusson, A; Robles, C; Casabonne, D; Benavente, Y; Becker, N; Brennan, P; Foretova, L; Maynadié, M; Staines, A; Nieters, A; Cocco, P; de Sanjosé, S.
Afiliación
  • Costas L; 1] Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, 08908 Barcelona, Spain [2] Department of Medicine, University of Barcelona, 08036 Barcelona, Spain [3] CIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain.
  • Infante-Rivard C; Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montréal, QC, Canada H3A 1A2.
  • Zock JP; 1] CIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain [2] Netherlands Institute for Health Services Research (NIVEL), 3500 Utrecht, The Netherlands [3] Centre for Research in Environmental Epidemiology (CREAL), 08003 Barcelona, Spain [4] Universitat Pompeu Fabra (UPF), 08003 Barcelona, Sp
  • Van Tongeren M; Centre for Human Exposure Science (CHES), Institute of Occupational Medicine, EH14 4AP Edinburgh, UK.
  • Boffetta P; Tisch Cancer Institute and Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, 10029 NY, USA.
  • Cusson A; Centre de Recherche, CHU Sainte-Justine, Montréal, QC, Canada H3T 1C4.
  • Robles C; Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, 08908 Barcelona, Spain.
  • Casabonne D; 1] Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, 08908 Barcelona, Spain [2] CIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain.
  • Benavente Y; 1] Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, 08908 Barcelona, Spain [2] CIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain.
  • Becker N; Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
  • Brennan P; IARC, International Agency for Research on Cancer, 69372 Lyon, France.
  • Foretova L; Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute and MF MU, 65653 Brno, Czech Republic.
  • Maynadié M; Biological Hematology Unit, CRB Ferdinand Cabanne, Universitary Hospital of Dijon and EA4184, University of Burgundy, EA 4184 Dijon, France.
  • Staines A; Public Health University College, Dublin, Ireland.
  • Nieters A; Centre of Chronic Immunodeficiency, Molecular Epidemiology, University Medical Center Freiburg, 79106 Freiburg, Germany.
  • Cocco P; Department of Public Health, Clinical and Molecular Medicine, Occupational Health Section, University of Cagliari, 09124 Cagliari, Italy.
  • de Sanjosé S; 1] Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, 08908 Barcelona, Spain [2] Department of Medicine, University of Barcelona, 08036 Barcelona, Spain [3] CIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain.
Br J Cancer ; 112(7): 1251-6, 2015 Mar 31.
Article en En | MEDLINE | ID: mdl-25742473
ABSTRACT

BACKGROUND:

Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma.

METHODS:

We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study.

RESULTS:

Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women.

CONCLUSIONS:

Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Exposición Profesional / Disruptores Endocrinos / Linfoma / Enfermedades Profesionales Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2015 Tipo del documento: Article País de afiliación: España

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Exposición Profesional / Disruptores Endocrinos / Linfoma / Enfermedades Profesionales Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Br J Cancer Año: 2015 Tipo del documento: Article País de afiliación: España
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