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Structure activity relationship of substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-4).
Singh, Sheo B; Kaelin, David E; Wu, Jin; Miesel, Lynn; Tan, Christopher M; Meinke, Peter T; Olsen, David B; Lagrutta, Armando; Wei, Changqing; Peng, Xuanjia; Wang, Xiu; Fukuda, Hideyuki; Kishii, Ryuta; Takei, Masaya; Shibata, Takeshi; Ohata, Kohei; Takano, Hisashi; Kurasaki, Haruaki; Takeuchi, Tomoko; Nishimura, Akinori; Fukuda, Yasumichi.
Afiliación
  • Singh SB; Merck Research Laboratories, Kenilworth, NJ 07033, United States. Electronic address: sheo.singh.215@gmail.com.
  • Kaelin DE; Merck Research Laboratories, Kenilworth, NJ 07033, United States.
  • Wu J; Merck Research Laboratories, Kenilworth, NJ 07033, United States.
  • Miesel L; Merck Research Laboratories, Kenilworth, NJ 07033, United States.
  • Tan CM; Merck Research Laboratories, Kenilworth, NJ 07033, United States.
  • Meinke PT; Merck Research Laboratories, Kenilworth, NJ 07033, United States.
  • Olsen DB; Merck Research Laboratories, West Point, PA 19486, United States.
  • Lagrutta A; Merck Research Laboratories, West Point, PA 19486, United States.
  • Wei C; WuXi AppTec, Shanghai, People's Republic of China.
  • Peng X; WuXi AppTec, Shanghai, People's Republic of China.
  • Wang X; WuXi AppTec, Shanghai, People's Republic of China.
  • Fukuda H; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Kishii R; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Takei M; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Shibata T; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Ohata K; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Takano H; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Kurasaki H; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Takeuchi T; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Nishimura A; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan.
  • Fukuda Y; Kyorin Pharmaceutical Co., Ltd, 2399-1, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan. Electronic address: yasumichi.fukuda@gmail.com.
Bioorg Med Chem Lett ; 25(11): 2409-15, 2015 Jun 01.
Article en En | MEDLINE | ID: mdl-25911300
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Staphylococcus aureus / ADN-Topoisomerasas / Inhibidores de Topoisomerasa Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Staphylococcus aureus / ADN-Topoisomerasas / Inhibidores de Topoisomerasa Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido