Time-dependent variation of HLA-antigen-frequencies in HIV-1-infection (1983-1988).
Tissue Antigens
; 34(3): 164-9, 1989 Sep.
Article
en En
| MEDLINE
| ID: mdl-2595721
ABSTRACT
In a 5-year-study of HLA-phenotypes in 411 HIV-1-infected individuals, a progressive decrease of the formerly elevated frequency of HLA-DR5 has been observed. HLA-DR3 seems to have a protective effect. These results are discussed with respect to the mimicry-hypothesis of HLA and disease associations. Further preliminary results indicate that HIV-associated Kaposi's sarcoma could be associated with HLA-A28, and therefore might be a different etiologic entity than HIV-infection alone.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Inmunodeficiencia Adquirida
/
VIH-1
/
Antígenos HLA
Tipo de estudio:
Observational_studies
Límite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Tissue Antigens
Año:
1989
Tipo del documento:
Article