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Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.
Su, Boyang; Kabinejadian, Foad; Phang, Hui Qun; Kumar, Gideon Praveen; Cui, Fangsen; Kim, Sangho; Tan, Ru San; Hon, Jimmy Kim Fatt; Allen, John Carson; Leo, Hwa Liang; Zhong, Liang.
Afiliación
  • Su B; National Heart Research Institute of Singapore, National Heart Centre Singapore, Singapore, Singapore.
  • Kabinejadian F; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
  • Phang HQ; Department of Surgery, National University of Singapore, Singapore, Singapore.
  • Kumar GP; Institute of High Performance Computing, ASTAR, Singapore, Singapore.
  • Cui F; Institute of High Performance Computing, ASTAR, Singapore, Singapore.
  • Kim S; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
  • Tan RS; National Heart Research Institute of Singapore, National Heart Centre Singapore, Singapore, Singapore.
  • Hon JK; Department of Surgery, National University of Singapore, Singapore, Singapore.
  • Allen JC; Duke-NUS Graduate Medical School, Singapore, Singapore.
  • Leo HL; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore.
  • Zhong L; National Heart Research Institute of Singapore, National Heart Centre Singapore, Singapore, Singapore; Duke-NUS Graduate Medical School, Singapore, Singapore.
PLoS One ; 10(5): e0126315, 2015.
Article en En | MEDLINE | ID: mdl-25961285
This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The rigid leaflet rotation was driven by the transmitral flow and hence the leaflet dynamics were solved using fluid-structure interaction approach. The simulation results showed that the bileaflet mechanical heart valve at the mitral position behaved similarly to that at the aortic position. Sudden area expansion near the aortic root initiated a clockwise anterior vortex, and the continuous injection of flow through the orifice resulted in further growth of the anterior vortex during diastole, which dominated the intraventricular flow. This flow feature is beneficial to preserving the flow momentum and redirecting the blood flow towards the aortic valve. To the best of our knowledge, this is the first attempt to numerically model intraventricular flow with the mechanical heart valve incorporated at the mitral position using a fluid-structure interaction approach. This study facilitates future patient-specific studies.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prótesis Valvulares Cardíacas / Función Ventricular / Diástole / Ventrículos Cardíacos / Hemodinámica / Modelos Cardiovasculares Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Prótesis Valvulares Cardíacas / Función Ventricular / Diástole / Ventrículos Cardíacos / Hemodinámica / Modelos Cardiovasculares Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2015 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos