Dysbiosis and Immune Dysregulation in Outer Space.
Int Rev Immunol
; 35(1): 67-82, 2016.
Article
en En
| MEDLINE
| ID: mdl-25970037
ABSTRACT
In space, the lifestyle, relative sterility of spaceship and extreme environmental stresses, such as microgravity and cosmic radiation, can compromise the balance between human body and human microbiome. An astronaut's body during spaceflight encounters increased risk for microbial infections and conditions because of immune dysregulation and altered microbiome, i.e. dysbiosis. This risk is further heightened by increase in virulence of pathogens in microgravity. Health status of astronauts might potentially benefit from maintaining a healthy microbiome by specifically managing their diet on space in addition to probiotic therapies. This review focuses on the current knowledge/understanding of how spaceflight affects human immunity and microbiome.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vuelo Espacial
/
Ingravidez
/
Disbiosis
/
Microbioma Gastrointestinal
/
Inmunidad
Aspecto:
Patient_preference
Límite:
Humans
Idioma:
En
Revista:
Int Rev Immunol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos