Omega-3 Fatty Acid-Rich Parenteral Nutrition: Is It a Double-Edged Sword?
J Pediatr Gastroenterol Nutr
; 61(4): 469-71, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-25988562
ABSTRACT
Parenteral nutrition (PN) has been strongly associated with intestinal failure-associated liver disease. Cholestasis, liver steatosis, and liver fibrosis are features of this liver injury, which can progress to end stage liver disease. Omega-3 fatty acid rich PN has been shown to alleviate cholestasis and steatosis. There have been reports although suggesting that it may not be able to arrest or reverse the progression to liver fibrosis. In this article, we develop a hypothesis of the mechanism of how Ω-3 fatty acid rich PN may influence the progression of fibrosis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácidos Grasos Omega-3
/
Nutrición Parenteral
/
Diacilglicerol O-Acetiltransferasa
/
Emulsiones Grasas Intravenosas
/
Enfermedad del Hígado Graso no Alcohólico
/
Cirrosis Hepática
/
Modelos Biológicos
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Pediatr Gastroenterol Nutr
Año:
2015
Tipo del documento:
Article
País de afiliación:
Reino Unido