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Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.
Hussein, D; Starr, A; Heikal, L; McNeill, E; Channon, K M; Brown, P R; Sutton, B J; McDonnell, J M; Nandi, M.
Afiliación
  • Hussein D; Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • Starr A; Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • Heikal L; Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • McNeill E; British Heart Foundation Centre of Research Excellence, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
  • Channon KM; British Heart Foundation Centre of Research Excellence, Division of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
  • Brown PR; The Randall Division of Cell and Molecular Biophysics, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • Sutton BJ; The Randall Division of Cell and Molecular Biophysics, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • McDonnell JM; The Randall Division of Cell and Molecular Biophysics, Faculty of Life Sciences & Medicine, King's College London, London, UK.
  • Nandi M; Institute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Br J Pharmacol ; 172(16): 4146-57, 2015 Aug.
Article en En | MEDLINE | ID: mdl-26014146
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenilalanina / Biopterinas / Péptidos y Proteínas de Señalización Intracelular / GTP Ciclohidrolasa Límite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenilalanina / Biopterinas / Péptidos y Proteínas de Señalización Intracelular / GTP Ciclohidrolasa Límite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido