Corpus callosum area and brain volume in autism spectrum disorder: quantitative analysis of structural MRI from the ABIDE database.
J Autism Dev Disord
; 45(10): 3107-14, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-26043845
ABSTRACT
Reduced corpus callosum area and increased brain volume are two commonly reported findings in autism spectrum disorder (ASD). We investigated these two correlates in ASD and healthy controls using T1-weighted MRI scans from the Autism Brain Imaging Data Exchange (ABIDE). Automated methods were used to segment the corpus callosum and intracranial region. No difference in the corpus callosum area was found between ASD participants and healthy controls (ASD 598.53 ± 109 mm(2); control 596.82 ± 102 mm(2); p = 0.76). The ASD participants had increased intracranial volume (ASD 1,508,596 ± 170,505 mm(3); control 1,482,732 ± 150,873.5 mm(3); p = 0.042). No evidence was found for overall ASD differences in the corpus callosum subregions.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cuerpo Calloso
/
Trastorno del Espectro Autista
Tipo de estudio:
Observational_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Autism Dev Disord
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos