Nanobodies and recombinant binders in cell biology.
J Cell Biol
; 209(5): 633-44, 2015 Jun 08.
Article
en En
| MEDLINE
| ID: mdl-26056137
ABSTRACT
Antibodies are key reagents to investigate cellular processes. The development of recombinant antibodies and binders derived from natural protein scaffolds has expanded traditional applications, such as immunofluorescence, binding arrays, and immunoprecipitation. In addition, their small size and high stability in ectopic environments have enabled their use in all areas of cell research, including structural biology, advanced microscopy, and intracellular expression. Understanding these novel reagents as genetic modules that can be integrated into cellular pathways opens up a broad experimental spectrum to monitor and manipulate cellular processes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Anticuerpos de Dominio Único
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Cell Biol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Alemania