Incidence and survival of childhood central nervous system tumors: A report of the regional registry of childhood cancers in Auvergne-Limousin.
Neurochirurgie
; 61(4): 237-43, 2015 Aug.
Article
en En
| MEDLINE
| ID: mdl-26123613
ABSTRACT
INTRODUCTION:
Central nervous system tumors (CNST) are the most lethal of solid tumors in childhood cancer. PATIENTS ANDMETHODS:
We report incidence and survival data for all CNST (International Classification of Diseases for Oncology third edition, category III or Xa) recorded in children under 15 years of age by the Auvergne-Limousin cancer registry for the period 1986-2009.RESULTS:
Annual incidence of all CNST was 3.27 per 100,000 and the male to female ratio was 0.95. Over 45.0% of CNST were glial. Astrocytomas (36.2%) showed the highest incidence for each age group except between 1 and 4 years where embryonal tumors were more common. For all CNST, no significant variation in incidence over time was observed for the evaluated period of 23 years (annual percent change -0.4%, 95% CI, [-2.8-2.1]). Globally, 5 years overall survival was 67% [59-73] and had increased by more than 16% between 1986-1999 and 2000-2009, mainly due to better survival for astrocytomas, other gliomas, ependymomas and choroid plexus tumors (P=0.01).CONCLUSION:
We report that the incidence of CNST in Auvergne-Limousin is similar to that in the literature and did not increase between 1986 and 2009. In addition, 5 years overall survival increased after 1999, especially for surgically treatable tumors.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Astrocitoma
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Neoplasias del Sistema Nervioso Central
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Ependimoma
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Glioma
Tipo de estudio:
Diagnostic_studies
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Incidence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adolescent
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Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Revista:
Neurochirurgie
Año:
2015
Tipo del documento:
Article
Pais de publicación:
FR
/
FRANCE
/
FRANCIA
/
FRANÇA