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Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis.
Duckworth, Carrie A; Guimond, Scott E; Sindrewicz, Paulina; Hughes, Ashley J; French, Neil S; Lian, Lu-Yun; Yates, Edwin A; Pritchard, D Mark; Rhodes, Jonathan M; Turnbull, Jeremy E; Yu, Lu-Gang.
Afiliación
  • Duckworth CA; Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
  • Guimond SE; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
  • Sindrewicz P; Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
  • Hughes AJ; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
  • French NS; Diamond Light Source Ltd, Harwell Innovation Campus, Didcot, United Kingdom.
  • Lian LY; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
  • Yates EA; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
  • Pritchard DM; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
  • Rhodes JM; Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
  • Turnbull JE; Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
  • Yu LG; Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Oncotarget ; 6(27): 23671-87, 2015 Sep 15.
Article en En | MEDLINE | ID: mdl-26160844
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heparina / Galectina 3 / Neoplasias Pulmonares Límite: Animals / Female / Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heparina / Galectina 3 / Neoplasias Pulmonares Límite: Animals / Female / Humans Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos