Blood hypercoagulability and systemic inflammation in horses with heaves.
Vet J
; 206(1): 105-7, 2015 Oct.
Article
en En
| MEDLINE
| ID: mdl-26164529
ABSTRACT
As inflammation and coagulation are intertwined processes, the efficiency of blood coagulation of heaves-affected horses and controls were compared in an observational case-control study, using thrombelastography. In experiment 1 (Exacerbation, six heaves, five controls), horses were housed indoors and fed hay. Thrombelastography, functional fibrinogen, platelet count, hematology, and antithrombin were measured. In experiment 2 (Remission, eight heaves, 11 controls), horses were housed in a low-dust environment for at least a month when thrombelastography was performed. Heaves-affected horses in exacerbation had greater maximum amplitude and higher functional fibrinogen than controls. Heaves-affected horses in clinical remission had greater maximum amplitude than controls. The hypercoagulable state and systemic inflammation of horses with heaves may be a consequence of pulmonary inflammation and may contribute to the perpetuation of airway dysfunction.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trombofilia
/
Enfermedad Pulmonar Obstructiva Crónica
/
Enfermedades de los Caballos
/
Inflamación
Tipo de estudio:
Observational_studies
Límite:
Animals
Idioma:
En
Revista:
Vet J
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2015
Tipo del documento:
Article