Nitroreductase-triggered activation of a novel caged fluorescent probe obtained from methylene blue.
Chem Commun (Camb)
; 51(64): 12787-90, 2015 Aug 18.
Article
en En
| MEDLINE
| ID: mdl-26165999
A near-infrared fluorescent probe based on methylene blue (p-NBMB) was developed for the detection of nitroreductase. Conjugating methylene blue with a p-nitrobenzyl moiety enables it to be activated by nitroreductase-catalyzed 1,6-elimination, resulting in the release of an active methylene blue fluorophore.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Nitrorreductasas
/
Colorantes Fluorescentes
/
Azul de Metileno
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Reino Unido