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Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia.
Li, June; van der Wal, Dianne E; Zhu, Guangheng; Xu, Miao; Yougbare, Issaka; Ma, Li; Vadasz, Brian; Carrim, Naadiya; Grozovsky, Renata; Ruan, Min; Zhu, Lingyan; Zeng, Qingshu; Tao, Lili; Zhai, Zhi-min; Peng, Jun; Hou, Ming; Leytin, Valery; Freedman, John; Hoffmeister, Karin M; Ni, Heyu.
Afiliación
  • Li J; 1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [2] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [3] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, To
  • van der Wal DE; 1] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [2] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8 [3] Canadian Blood Services, Ottawa, Ontario, Canada K1G 4J5.
  • Zhu G; 1] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [2] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8.
  • Xu M; 1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [2] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [3] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, To
  • Yougbare I; 1] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [2] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8 [3] Canadian Blood Services, Ottawa, Ontario, Canada K1G 4J5.
  • Ma L; 1] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [2] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8 [3] Canadian Blood Services, Ottawa, Ontario, Canada K1G 4J5.
  • Vadasz B; 1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [2] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [3] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, To
  • Carrim N; 1] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [2] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8.
  • Grozovsky R; Translational Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Ruan M; Department of Hematology, Anhui Medical University, Hefei 230032, China.
  • Zhu L; Department of Hematology, Anhui Medical University, Hefei 230032, China.
  • Zeng Q; Department of Hematology, Anhui Medical University, Hefei 230032, China.
  • Tao L; Department of Hematology, Anhui Medical University, Hefei 230032, China.
  • Zhai ZM; Department of Hematology, Anhui Medical University, Hefei 230032, China.
  • Peng J; Department of Hematology, Qilu Hospital, Shandong University, Jinan 250012, China.
  • Hou M; Department of Hematology, Qilu Hospital, Shandong University, Jinan 250012, China.
  • Leytin V; 1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [2] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [3] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, To
  • Freedman J; 1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [2] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [3] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, To
  • Hoffmeister KM; Translational Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Ni H; 1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [2] Toronto Platelet Immunobiology Group, Toronto, Ontario, Canada M5B 1W8 [3] Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science of St. Michael's Hospital, To
Nat Commun ; 6: 7737, 2015 Jul 17.
Article en En | MEDLINE | ID: mdl-26185093
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Púrpura Trombocitopénica Idiopática / Complejo GPIIb-IIIa de Glicoproteína Plaquetaria / Complejo GPIb-IX de Glicoproteína Plaquetaria / Integrina beta3 / Anticuerpos Monoclonales de Origen Murino / Neuraminidasa Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Tonga
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Púrpura Trombocitopénica Idiopática / Complejo GPIIb-IIIa de Glicoproteína Plaquetaria / Complejo GPIb-IX de Glicoproteína Plaquetaria / Integrina beta3 / Anticuerpos Monoclonales de Origen Murino / Neuraminidasa Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Tonga