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Discovery of Tyk2 inhibitors via the virtual site-directed fragment-based drug design.
Jang, Woo Dae; Kim, Jun-Tae; Son, Hoon Young; Park, Seung Yeon; Cho, Young Sik; Koo, Tae-sung; Lee, Hyuk; Kang, Nam Sook.
Afiliación
  • Jang WD; Graduate School of New Drug Discovery and Development, Chungnam National University, Daehakno 99, Yuseong-gu, Daejeon 305-764, Republic of Korea.
  • Kim JT; Graduate School of New Drug Discovery and Development, Chungnam National University, Daehakno 99, Yuseong-gu, Daejeon 305-764, Republic of Korea.
  • Son HY; Research Center for Medicinal Chemistry, Drug Discovery Division, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 305-600, Republic of Korea.
  • Park SY; College of Pharmacy, Keimyung University, 1000 Sindang-dong, Dalseo-Gu, Daegu, Republic of Korea.
  • Cho YS; College of Pharmacy, Keimyung University, 1000 Sindang-dong, Dalseo-Gu, Daegu, Republic of Korea.
  • Koo TS; Graduate School of New Drug Discovery and Development, Chungnam National University, Daehakno 99, Yuseong-gu, Daejeon 305-764, Republic of Korea.
  • Lee H; Research Center for Medicinal Chemistry, Drug Discovery Division, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 305-600, Republic of Korea. Electronic address: leeh@krict.re.kr.
  • Kang NS; Graduate School of New Drug Discovery and Development, Chungnam National University, Daehakno 99, Yuseong-gu, Daejeon 305-764, Republic of Korea. Electronic address: nskang@cnu.ac.kr.
Bioorg Med Chem Lett ; 25(18): 3947-52, 2015 Sep 15.
Article en En | MEDLINE | ID: mdl-26231159
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inhibidores de Proteínas Quinasas / TYK2 Quinasa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Inhibidores de Proteínas Quinasas / TYK2 Quinasa Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article Pais de publicación: Reino Unido