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Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative.
Scuotto, Maria; Rivieccio, Elisa; Varone, Alessia; Corda, Daniela; Bucci, Mariarosaria; Vellecco, Valentina; Cirino, Giuseppe; Virgilio, Antonella; Esposito, Veronica; Galeone, Aldo; Borbone, Nicola; Varra, Michela; Mayol, Luciano.
Afiliación
  • Scuotto M; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Rivieccio E; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Varone A; Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Corda D; Institute of Protein Biochemistry, National Research Council, Via Pietro Castellino 111, 80131 Naples, Italy.
  • Bucci M; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Vellecco V; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Cirino G; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Virgilio A; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Esposito V; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Galeone A; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
  • Borbone N; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy nicola.borbone@unina.it.
  • Varra M; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy varra@unina.it.
  • Mayol L; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, Naples, Italy.
Nucleic Acids Res ; 43(16): 7702-16, 2015 Sep 18.
Article en En | MEDLINE | ID: mdl-26250112
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aptámeros de Nucleótidos / Anticoagulantes / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aptámeros de Nucleótidos / Anticoagulantes / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nucleic Acids Res Año: 2015 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido