Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients.

Carboni, Lucia; Lattanzio, Francesca; Candeletti, Sanzio; Porcellini, Elisa; Raschi, Elena; Licastro, Federico; Romualdi, Patrizia

Carboni, Lucia; Lattanzio, Francesca; Candeletti, Sanzio; Porcellini, Elisa; Raschi, Elena; Licastro, Federico; Romualdi, Patrizia.

Afiliación

Carboni L; Department of Pharmacy and Biotechnology (FaBiT), Alma Mater Studiorum University of Bologna, Bologna, Italy. Electronic address: lucia.carboni4@unibo.it.
Lattanzio F; Department of Pharmacy and Biotechnology (FaBiT), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Candeletti S; Department of Pharmacy and Biotechnology (FaBiT), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Porcellini E; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Raschi E; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Licastro F; Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Romualdi P; Department of Pharmacy and Biotechnology (FaBiT), Alma Mater Studiorum University of Bologna, Bologna, Italy.

Neurosci Lett ; 605: 44-8, 2015 Sep 25.

Article en En | MEDLINE | ID: mdl-26275347

Asunto(s)

Enfermedad de Alzheimer/genética; Factor Neurotrófico Derivado del Encéfalo/genética; Leucocitos/metabolismo; Presenilina-1/genética; Sirtuina 1/genética; Anciano; Anciano de 80 o más Años; Enfermedad de Alzheimer/sangre; Biomarcadores/sangre; Factor Neurotrófico Derivado del Encéfalo/sangre; Estudios de Casos y Controles; Humanos; Masculino; Metilación; Presenilina-1/sangre; Regiones Promotoras Genéticas; Sirtuina 1/sangre

Palabras clave

Alzheimer disease; Biomarkers; Brain derived neurotrophic factor; DNA methylation; Presenilin 1; Sirtuin 1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor Neurotrófico Derivado del Encéfalo / Presenilina-1 / Sirtuina 1 / Enfermedad de Alzheimer / Leucocitos Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Humans / Male Idioma: En Revista: Neurosci Lett Año: 2015 Tipo del documento: Article Pais de publicación: Irlanda

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