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Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis.
Ndubaku, Chudi O; Crawford, Terry D; Chen, Huifen; Boggs, Jason W; Drobnick, Joy; Harris, Seth F; Jesudason, Rajiv; McNamara, Erin; Nonomiya, Jim; Sambrone, Amy; Schmidt, Stephen; Smyczek, Tanya; Vitorino, Philip; Wang, Lan; Wu, Ping; Yeung, Stacey; Chen, Jinhua; Chen, Kevin; Ding, Charles Z; Wang, Tao; Xu, Zijin; Gould, Stephen E; Murray, Lesley J; Ye, Weilan.
Afiliación
  • Ndubaku CO; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Crawford TD; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Chen H; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Boggs JW; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Drobnick J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Harris SF; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Jesudason R; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • McNamara E; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Nonomiya J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Sambrone A; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Schmidt S; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Smyczek T; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Vitorino P; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wang L; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wu P; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Yeung S; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Chen J; Wuxi Apptec Co., Ltd. , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China.
  • Chen K; Wuxi Apptec Co., Ltd. , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China.
  • Ding CZ; Wuxi Apptec Co., Ltd. , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China.
  • Wang T; Wuxi Apptec Co., Ltd. , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China.
  • Xu Z; Wuxi Apptec Co., Ltd. , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China.
  • Gould SE; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Murray LJ; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Ye W; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
ACS Med Chem Lett ; 6(8): 913-8, 2015 Aug 13.
Article en En | MEDLINE | ID: mdl-26288693
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos