The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis.

Evans, Joanna C; Mizrahi, Valerie

Evans, Joanna C; Mizrahi, Valerie.

Afiliación

Evans JC; South African Medical Research Council/National Health Laboratory Service/University of Cape Town Molecular Mycobacteriology Research Unit Cape Town, South Africa ; DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town Cape Town, South Africa.
Mizrahi V; South African Medical Research Council/National Health Laboratory Service/University of Cape Town Molecular Mycobacteriology Research Unit Cape Town, South Africa ; DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town Cape Town, South Africa.

Front Microbiol ; 6: 812, 2015.

Article en En | MEDLINE | ID: mdl-26300875

Palabras clave

Mycobacterium tuberculosis; drug discovery; hypomorphs; regulated gene expression; target validation; target-based whole cell screening

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2015 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Suiza

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