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Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer.
Goey, Andrew K L; Sissung, Tristan M; Peer, Cody J; Trepel, Jane B; Lee, Min-Jung; Tomita, Yusuke; Ehrlich, Sheryl; Bryla, Christine; Balasubramaniam, Sanjeeve; Piekarz, Richard; Steinberg, Seth M; Bates, Susan E; Figg, William D.
Afiliación
  • Goey AK; Clinical Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Sissung TM; Molecular Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Peer CJ; Clinical Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Trepel JB; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Lee MJ; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Tomita Y; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Ehrlich S; Molecular Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Bryla C; Medical Oncology Service, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Balasubramaniam S; Medical Oncology Service, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Piekarz R; Cancer Therapy Evaluation Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Steinberg SM; Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Bates SE; Medical Oncology Service, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Figg WD; Clinical Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
J Clin Pharmacol ; 56(4): 461-73, 2016 Apr.
Article en En | MEDLINE | ID: mdl-26313268
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfonamidas / Glucuronosiltransferasa / Ácidos Hidroxámicos / Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfonamidas / Glucuronosiltransferasa / Ácidos Hidroxámicos / Neoplasias Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Clin Pharmacol Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos