Physiology, production and action of progesterone.
Acta Obstet Gynecol Scand
; 94 Suppl 161: 8-16, 2015 Nov.
Article
en En
| MEDLINE
| ID: mdl-26358238
ABSTRACT
INTRODUCTION:
The aim of this article is to review the physiology of progesterone and focus on its physiological actions on tissues such as endometrium, uterus, mammary gland, cardiovascular system, central nervous system and bones. In the last decades, the interest of researchers has focused on the role of progesterone in genomic and non-genomic receptor mechanisms. MATERIALS ANDMETHODS:
We searched PubMed up to December 2014 for publications on progesterone/steroidogenesis. RESULTS ANDCONCLUSIONS:
A better understanding of the biological genomic and non-genomic receptor mechanisms could enable us in the near future to obtain a more comprehensive knowledge of the safety and efficacy of this agent during hormone replacement therapy (natural progesterone), in vitro fertilization (water-soluble subcutaneous progesterone), in traumatic brain injury, Alzheimer's disease and diabetic neuropathy, even though further clinical studies are needed to prove its usefulness.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Progesterona
/
Receptores de Progesterona
/
Ciclo Menstrual
Tipo de estudio:
Systematic_reviews
Límite:
Female
/
Humans
Idioma:
En
Revista:
Acta Obstet Gynecol Scand
Año:
2015
Tipo del documento:
Article
País de afiliación:
Italia