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Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).
Min, Xiaoshan; Ungureanu, Daniela; Maxwell, Sarah; Hammarén, Henrik; Thibault, Steve; Hillert, Ellin-Kristina; Ayres, Merrill; Greenfield, Brad; Eksterowicz, John; Gabel, Chris; Walker, Nigel; Silvennoinen, Olli; Wang, Zhulun.
Afiliación
  • Min X; Departments of Therapeutic Discovery, Amgen Inc., South San Francisco, California 94080.
  • Ungureanu D; the Institute of Biomedical Technology, University of Tampere, 33014 Tampere, Finland.
  • Maxwell S; Departments of Inflammation, Amgen Inc., South San Francisco, California 94080.
  • Hammarén H; the School of Medicine, University of Tampere, 33014 Tampere, Finland.
  • Thibault S; Departments of Therapeutic Discovery, Amgen Inc., South San Francisco, California 94080.
  • Hillert EK; the Institute of Biomedical Technology, University of Tampere, 33014 Tampere, Finland.
  • Ayres M; Departments of Therapeutic Discovery, Amgen Inc., South San Francisco, California 94080.
  • Greenfield B; Departments of Inflammation, Amgen Inc., South San Francisco, California 94080.
  • Eksterowicz J; Departments of Therapeutic Discovery, Amgen Inc., South San Francisco, California 94080.
  • Gabel C; Departments of Inflammation, Amgen Inc., South San Francisco, California 94080.
  • Walker N; Departments of Therapeutic Discovery, Amgen Inc., South San Francisco, California 94080.
  • Silvennoinen O; the School of Medicine, University of Tampere, 33014 Tampere, Finland; Department of Clinical Hematology, Tampere University Hospital, 33520 Tampere, Finland. Electronic address: olli.silvennoinen@uta.fi.
  • Wang Z; Departments of Therapeutic Discovery, Amgen Inc., South San Francisco, California 94080. Electronic address: zwang@amgen.com.
J Biol Chem ; 290(45): 27261-27270, 2015 Nov 06.
Article en En | MEDLINE | ID: mdl-26359499
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: TYK2 Quinasa Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: TYK2 Quinasa Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article Pais de publicación: Estados Unidos