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Molecular mechanism of a specific capsid binder resistance caused by mutations outside the binding pocket.
Braun, Heike; Kirchmair, Johannes; Williamson, Mark J; Makarov, Vadim A; Riabova, Olga B; Glen, Robert C; Sauerbrei, Andreas; Schmidtke, Michaela.
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  • Braun H; Jena University Hospital, School of Medicine, Department of Virology and Antiviral Therapy, Hans-Knöll-Str. 2, 07745 Jena, Germany; Department of Clinical Pharmacy and Pharmacotherapy, Institute of Pharmacy, Martin-Luther-University Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, D-06120 Halle (Saale)
  • Kirchmair J; Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom; University of Hamburg, Center for Bioinformatics, Bundesstraße 43, 20146 Hamburg, Germany.
  • Williamson MJ; Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
  • Makarov VA; Bakh Institute of Biochemistry, Leninsky pr., 33-2, Moscow 119071, Russia.
  • Riabova OB; Bakh Institute of Biochemistry, Leninsky pr., 33-2, Moscow 119071, Russia.
  • Glen RC; Centre for Molecular Informatics, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom.
  • Sauerbrei A; Jena University Hospital, School of Medicine, Department of Virology and Antiviral Therapy, Hans-Knöll-Str. 2, 07745 Jena, Germany.
  • Schmidtke M; Jena University Hospital, School of Medicine, Department of Virology and Antiviral Therapy, Hans-Knöll-Str. 2, 07745 Jena, Germany. Electronic address: michaela.schmidtke@med.uni-jena.de.
Antiviral Res ; 123: 138-45, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26391975
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Enterovirus Humano B / Mutación Missense / Farmacorresistencia Viral / Proteínas de la Cápside Límite: Humans Idioma: En Revista: Antiviral Res Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Enterovirus Humano B / Mutación Missense / Farmacorresistencia Viral / Proteínas de la Cápside Límite: Humans Idioma: En Revista: Antiviral Res Año: 2015 Tipo del documento: Article Pais de publicación: Países Bajos