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An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking.
Schneeberger, Kerstin; Vogel, Georg F; Teunissen, Hans; van Ommen, Domenique D; Begthel, Harry; El Bouazzaoui, Layla; van Vugt, Anke H M; Beekman, Jeffrey M; Klumperman, Judith; Müller, Thomas; Janecke, Andreas; Gerner, Patrick; Huber, Lukas A; Hess, Michael W; Clevers, Hans; van Es, Johan H; Nieuwenhuis, Edward E S; Middendorp, Sabine.
Afiliación
  • Schneeberger K; Division of Paediatrics, Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre (UMC) Utrecht, 3584 EA, Utrecht, The Netherlands;
  • Vogel GF; Division of Cell Biology, Biocenter, Medical University Innsbruck, A-6020 Innsbruck, Austria; Division of Histology and Embryology, Medical University Innsbruck, A-6020 Innsbruck Austria;
  • Teunissen H; Division of Paediatrics, Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre (UMC) Utrecht, 3584 EA, Utrecht, The Netherlands;
  • van Ommen DD; Laboratory of Translational Immunology and Department of Paediatric Pulmonology, Wilhelmina Children's Hospital, UMC Utrecht, 3584 EA, Utrecht, The Netherlands;
  • Begthel H; Hubrecht Institute for Developmental Biology and Stem Cell Research, Royal Dutch Academy of Sciences and UMC Utrecht, 3584 CT, Utrecht, The Netherlands;
  • El Bouazzaoui L; Division of Paediatrics, Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre (UMC) Utrecht, 3584 EA, Utrecht, The Netherlands;
  • van Vugt AH; Division of Paediatrics, Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre (UMC) Utrecht, 3584 EA, Utrecht, The Netherlands;
  • Beekman JM; Laboratory of Translational Immunology and Department of Paediatric Pulmonology, Wilhelmina Children's Hospital, UMC Utrecht, 3584 EA, Utrecht, The Netherlands;
  • Klumperman J; Department of Cell Biology and The Cell Microscopy Centre, UMC Utrecht, 3584 CX, Utrecht, The Netherlands;
  • Müller T; Department of Pediatrics I, Medical University Innsbruck, A-6020 Innsbruck, Austria;
  • Janecke A; Department of Pediatrics I, Medical University Innsbruck, A-6020 Innsbruck, Austria; Division of Human Genetics, Medical University Innsbruck, A-6020 Innsbruck, Austria;
  • Gerner P; Zentrum für Kinder- und Jugendmedizin, Universitätsklinikum Freiburg, 79106 Freiburg, Germany.
  • Huber LA; Division of Cell Biology, Biocenter, Medical University Innsbruck, A-6020 Innsbruck, Austria;
  • Hess MW; Division of Histology and Embryology, Medical University Innsbruck, A-6020 Innsbruck Austria;
  • Clevers H; Hubrecht Institute for Developmental Biology and Stem Cell Research, Royal Dutch Academy of Sciences and UMC Utrecht, 3584 CT, Utrecht, The Netherlands; h.clevers@hubrecht.eu s.middendorp@umcutrecht.nl.
  • van Es JH; Hubrecht Institute for Developmental Biology and Stem Cell Research, Royal Dutch Academy of Sciences and UMC Utrecht, 3584 CT, Utrecht, The Netherlands;
  • Nieuwenhuis EE; Division of Paediatrics, Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre (UMC) Utrecht, 3584 EA, Utrecht, The Netherlands;
  • Middendorp S; Division of Paediatrics, Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Centre (UMC) Utrecht, 3584 EA, Utrecht, The Netherlands; h.clevers@hubrecht.eu s.middendorp@umcutrecht.nl.
Proc Natl Acad Sci U S A ; 112(40): 12408-13, 2015 Oct 06.
Article en En | MEDLINE | ID: mdl-26392529
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Miosina Tipo V / Síndromes de Malabsorción / Microvellosidades / Mucolipidosis Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Miosina Tipo V / Síndromes de Malabsorción / Microvellosidades / Mucolipidosis Límite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article