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Shear-Induced Detachment of Polystyrene Beads from SAM-Coated Surfaces.
Cho, Kwun Lun; Rosenhahn, Axel; Thelen, Richard; Grunze, Michael; Lobban, Matthew; Karahka, Markus Leopold; Kreuzer, H Jürgen.
Afiliación
  • Cho KL; Institute for Functional Interfaces, Karlsruhe Institute of Technology , Kaiserstraße 12, 76131 Karlsruhe, Germany.
  • Rosenhahn A; Analytical Chemistry-Biointerfaces, Ruhr-University Bochum , 44801 Bochum, Germany.
  • Thelen R; Institute of Microstructure Technology, Karlsruhe Institute of Technology , Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
  • Grunze M; Institute for Functional Interfaces, Karlsruhe Institute of Technology , Kaiserstraße 12, 76131 Karlsruhe, Germany.
  • Lobban M; Applied Physical Chemistry, University of Heidelberg , D-69120 Heidelberg, Germany.
  • Karahka ML; Department of Physics and Atmospheric Science, Dalhousie University , Halifax, Nova Scotia B3H 3J5, Canada.
  • Kreuzer HJ; Department of Physics and Atmospheric Science, Dalhousie University , Halifax, Nova Scotia B3H 3J5, Canada.
Langmuir ; 31(40): 11105-12, 2015 Oct 13.
Article en En | MEDLINE | ID: mdl-26401759
ABSTRACT
In this work we experimentally and theoretically analyze the detachment of microscopic polystyrene beads from different self-assembled monolayer (SAM) surfaces in a shear flow in order to develop a mechanistic model for the removal of cells from surfaces. The detachment of the beads from the surface is treated as a thermally activated process applying an Arrhenius Ansatz to determine the activation barrier and attempt frequency of the rate determing step in bead removal. The statistical analysis of the experimental shear detachment data obtained in phosphate-buffered saline buffer results in an activation energy around 20 kJ/mol, which is orders of magnitude lower than the adhesion energy measured by atomic force microscopy (AFM). The same order of magnitude for the adhesion energy measured by AFM is derived from ab initio calculations of the van der Waals interaction energy between the polystyrene beads and the SAM-covered gold surface. We conclude that the rate determing step for detachment of the beads is the initiation of rolling on the surface (overcoming static friction) and not physical detachment, i.e., lifting the particle off the surface.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliestirenos / Resistencia al Corte Idioma: En Revista: Langmuir Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliestirenos / Resistencia al Corte Idioma: En Revista: Langmuir Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Alemania