Spotlighted Brains: Optogenetic Activation and Silencing of Neurons.

Kianianmomeni, Arash; Hallmann, Armin

Kianianmomeni, Arash; Hallmann, Armin.

Afiliación

Kianianmomeni A; Department of Cellular and Developmental Biology of Plants, University of Bielefeld, Universitätsstrasse 25, D-33615 Bielefeld, Germany. Electronic address: kianian@uni-bielefeld.de.
Hallmann A; Department of Cellular and Developmental Biology of Plants, University of Bielefeld, Universitätsstrasse 25, D-33615 Bielefeld, Germany.

Trends Biochem Sci ; 40(11): 624-627, 2015 Nov.

Article en En | MEDLINE | ID: mdl-26433473

ABSTRACT

ABSTRACT

Optogenetics is revolutionizing cell biology and neuroscience research by allowing precise biochemical control of neuronal activity through light-activated channels. Light-induced ion transporters have been used extensively for cellular activation, and now light-gated inhibitory channels have been discovered. These represent a key new tool to elucidate the molecular mechanisms underlying neurological and neuropsychiatric disorders.

Asunto(s)

Encéfalo/fisiología; Luz; Neuronas/fisiología; Optogenética; Animales

Palabras clave

Channelrhodopsins; Optical neuronal silencers; Optogenetics; Rhodopsin-like photoreceptors; Synthetic biology

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Optogenética / Luz / Neuronas Límite: Animals Idioma: En Revista: Trends Biochem Sci Año: 2015 Tipo del documento: Article

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