Normal mast cell numbers in the tissues of AhR-deficient mice.
Exp Dermatol
; 25(1): 62-3, 2016 Jan.
Article
en En
| MEDLINE
| ID: mdl-26443189
ABSTRACT
The transcription factor aryl hydrocarbon receptor (AhR) acts as an immunomodulatory molecule in several immune cell lineages. Recently, it has been implicated in development and maintenance of immune cells in barrier tissues such as skin and mucosa. To investigate its role on mast cell development and maintenance in skin, peritoneal exudate cells (PECs) and lymph nodes, we studied in depth their phenotype in AhR-deficient mice. Our findings do not provide any evidence for a suspected role of the AhR in mast cell homeostasis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Receptores de Hidrocarburo de Aril
/
Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico
/
Mastocitos
Límite:
Animals
Idioma:
En
Revista:
Exp Dermatol
Asunto de la revista:
DERMATOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Alemania