Analysis of peripapillary choroidal thickness in non-arteritic anterior ischaemic optic neuropathy.
Br J Ophthalmol
; 100(7): 891-896, 2016 Jul.
Article
en En
| MEDLINE
| ID: mdl-26453640
ABSTRACT
PURPOSE:
To analyse peripapillary choroidal thickness (PCT) in non-arteritic ischaemic optic neuropathy (NAION).METHODS:
28 patients diagnosed with NAION (37 affected and 19 unaffected eyes) and 38 disease-free control individuals (38 eyes) were analysed using enhanced-depth imaging of spectral-domain optical coherence tomography. A vertical and a horizontal raster scan centred on the optic nerve were obtained per eye. PCT was measured at the superior, inferior, nasal and temporal quadrants from the posterior edge of the retinal pigment epithelium to the choroid-sclera junction at 500â µm intervals up to 2000â µm away from the optic nerve. Statistical analysis was used to compare average PCT and to correlate PCT with other ocular and systemic parameters.RESULTS:
Mean PCT in NAION eyes and control group was 148.18±42.68â µm and 182.90±59.81â µm, respectively (p=0.005). Except for inferior PCT (p=0.158), superior, nasal and temporal PCT were significantly thinner in the NAION eyes than in the control group (p=0.006, 0.002 and 0.046). Thinner PCT, adjusted for refractive error, was associated with the diagnosis of NAION (p=0.048). Similarly, unaffected contralateral eyes showed a significant thinner PCT compared with the control group (p=0.024). Diagnosis of NAION was negatively associated with PCT in NAION eyes (p=0.008; OR 0.98; 95% CI 0.97 to 0.99) and in their contralateral unaffected eyes (p=0.043; OR 0.98; 95% CI 0.97 to 0.99).CONCLUSIONS:
Eyes affected by NAION and contralateral unaffected eyes showed significantly thinner PCT compared with disease-free control eyes after adjusting for refractive error.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Nervio Óptico
/
Agudeza Visual
/
Campos Visuales
/
Coroides
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Neuropatía Óptica Isquémica
/
Tomografía de Coherencia Óptica
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Br J Ophthalmol
Año:
2016
Tipo del documento:
Article
País de afiliación:
España