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Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L.
Parker, Erica N; Song, Jiangli; Kishore Kumar, G D; Odutola, Samuel O; Chavarria, Gustavo E; Charlton-Sevcik, Amanda K; Strecker, Tracy E; Barnes, Ashleigh L; Sudhan, Dhivya R; Wittenborn, Thomas R; Siemann, Dietmar W; Horsman, Michael R; Chaplin, David J; Trawick, Mary Lynn; Pinney, Kevin G.
Afiliación
  • Parker EN; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Song J; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Kishore Kumar GD; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Odutola SO; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798-7224, United States.
  • Chavarria GE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Charlton-Sevcik AK; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Strecker TE; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Barnes AL; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States.
  • Sudhan DR; Department of Radiation Oncology, University of Florida Health Cancer Center, Gainesville, FL 32610, United States.
  • Wittenborn TR; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
  • Siemann DW; Department of Radiation Oncology, University of Florida Health Cancer Center, Gainesville, FL 32610, United States; Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL 32610, United States.
  • Horsman MR; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
  • Chaplin DJ; OXiGENE, Inc., 701 Gateway Blvd, Suite 210, South San Francisco, CA 94080, United States.
  • Trawick ML; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798-7224, United States. Electronic address: Mary_Lynn_Trawick@baylor.edu.
  • Pinney KG; Department of Chemistry and Biochemistry, Baylor University, One Bear Place #97348, Waco, TX 76798-7348, United States; Institute of Biomedical Studies, Baylor University, One Bear Place #97224, Waco, TX 76798-7224, United States. Electronic address: Kevin_Pinney@baylor.edu.
Bioorg Med Chem ; 23(21): 6974-92, 2015 Nov 01.
Article en En | MEDLINE | ID: mdl-26462052
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiosemicarbazonas / Inhibidores de Cisteína Proteinasa / Catepsina L / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiosemicarbazonas / Inhibidores de Cisteína Proteinasa / Catepsina L / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido