Macromolecular cell surface engineering for accelerated and reversible cellular aggregation.

Amaral, Adérito J R; Pasparakis, George

Amaral, Adérito J R; Pasparakis, George.

Afiliación

Amaral AJ; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK. g.pasparakis@ucl.ac.uk.
Pasparakis G; UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK. g.pasparakis@ucl.ac.uk.

Chem Commun (Camb) ; 51(99): 17556-9, 2015 Dec 25.

Article en En | MEDLINE | ID: mdl-26478926

ABSTRACT

ABSTRACT

We report the synthesis of two simple copolymers that induce rapid cell aggregation within minutes in a fully reversible manner. The polymers can act as self-supporting "cellular glues" or as "drivers" of 3D cell spheroids/aggregates formation at minute concentrations.

Asunto(s)

Adhesión Celular; Sustancias Macromoleculares/química; Polímeros/química

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adhesión Celular / Sustancias Macromoleculares Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido

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