Additivity of the Stabilization Effect of Single Amino Acid Substitutions in Triple Mutants of Recombinant Formate Dehydrogenase from the Soybean Glycine max.

Alekseeva, A A; Kargov, I S; Kleimenov, S Yu; Savin, S S; Tishkov, V I

Alekseeva, A A; Kargov, I S; Kleimenov, S Yu; Savin, S S; Tishkov, V I.

Afiliación

Alekseeva AA; A.N.Bach Institute of Biochemistry, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninskiy Prospect, 33/2, Moscow,119071, Russia ; Innovations and High Technologies MSU Ltd, Tsimlyanskaya St., 16, Moscow, 109559, Russia.
Kargov IS; Innovations and High Technologies MSU Ltd, Tsimlyanskaya St., 16, Moscow, 109559, Russia ; Departament of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1/3, Moscow, 119991, Russia.
Kleimenov SY; A.N.Bach Institute of Biochemistry, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninskiy Prospect, 33/2, Moscow,119071, Russia ; N.K. Koltsov Institute of Developmental Biology of the Russian Academy of Sciences, Vavilova St., 26, Moscow, 119334, Russ
Savin SS; Innovations and High Technologies MSU Ltd, Tsimlyanskaya St., 16, Moscow, 109559, Russia ; Departament of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1/3, Moscow, 119991, Russia.
Tishkov VI; A.N.Bach Institute of Biochemistry, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninskiy Prospect, 33/2, Moscow,119071, Russia ; Innovations and High Technologies MSU Ltd, Tsimlyanskaya St., 16, Moscow, 109559, Russia ; Departament of Chemistry, M.V.

Acta Naturae ; 7(3): 55-64, 2015.

Article en En | MEDLINE | ID: mdl-26483960

Palabras clave

Glycine max; formate dehydrogenase; multi-point mutants; protein engineering; rational design; stability; stabilization; synergistic effect

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Acta Naturae Año: 2015 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Rusia

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