Research progress of acute coagulopathy of trauma-shock.
Chin J Traumatol
; 18(2): 95-7, 2015.
Article
en En
| MEDLINE
| ID: mdl-26511301
ABSTRACT
Acute coagulopathy of trauma-shock (ACoTS) occurs in 25% of patients with severe trauma in the early phase, and the mortality of those patients is four-fold higher than patients without coagulopathy. The pathophysiology of this complicated phenomenon has been focused on in recent years. Tissue injury and hypoperfusion, activated protein C and Complements play important roles in the early phase after trauma. While the use of blood products, hypothermia, acidosis and inflammation are the main mechanism in late phase. Supplementing coagulation factors and platelets to improve ACoTS are inefficient. Only positive resuscitation from shock and improving tissue hypoperfusion have expected benefits.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Choque Traumático
/
Trastornos de la Coagulación Sanguínea
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Chin J Traumatol
Asunto de la revista:
TRAUMATOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
China