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Double Copies of bla(KPC-3)::Tn4401a on an IncX3 Plasmid in Klebsiella pneumoniae Successful Clone ST512 from Italy.
Fortini, Daniela; Villa, Laura; Feudi, Claudia; Pires, João; Bonura, Celestino; Mammina, Caterina; Endimiani, Andrea; Carattoli, Alessandra.
Afiliación
  • Fortini D; Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
  • Villa L; Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
  • Feudi C; Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
  • Pires J; Institute for Infectious Diseases, University of Bern, Bern, Switzerland Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.
  • Bonura C; Department of Sciences for Health Promotion and Mother-Child Care G. D'Alessandro, University of Palermo, Palermo, Italy.
  • Mammina C; Department of Sciences for Health Promotion and Mother-Child Care G. D'Alessandro, University of Palermo, Palermo, Italy.
  • Endimiani A; Institute for Infectious Diseases, University of Bern, Bern, Switzerland.
  • Carattoli A; Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy Institute for Infectious Diseases, University of Bern, Bern, Switzerland alecara@iss.it.
Antimicrob Agents Chemother ; 60(1): 646-9, 2016 01.
Article en En | MEDLINE | ID: mdl-26525794
ABSTRACT
A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla(KPC) genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla(KPC-3) gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla(KPC-3)Tn4401a caused by intramolecular transposition events were detected in the plasmid.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plásmidos / Proteínas Bacterianas / Beta-Lactamasas / Elementos Transponibles de ADN / Regulación Bacteriana de la Expresión Génica / Farmacorresistencia Bacteriana Múltiple / Klebsiella pneumoniae País/Región como asunto: Europa Idioma: En Revista: Antimicrob Agents Chemother Año: 2016 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plásmidos / Proteínas Bacterianas / Beta-Lactamasas / Elementos Transponibles de ADN / Regulación Bacteriana de la Expresión Génica / Farmacorresistencia Bacteriana Múltiple / Klebsiella pneumoniae País/Región como asunto: Europa Idioma: En Revista: Antimicrob Agents Chemother Año: 2016 Tipo del documento: Article País de afiliación: Italia