Double Copies of bla(KPC-3)::Tn4401a on an IncX3 Plasmid in Klebsiella pneumoniae Successful Clone ST512 from Italy.
Antimicrob Agents Chemother
; 60(1): 646-9, 2016 01.
Article
en En
| MEDLINE
| ID: mdl-26525794
ABSTRACT
A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla(KPC) genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla(KPC-3) gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla(KPC-3)Tn4401a caused by intramolecular transposition events were detected in the plasmid.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plásmidos
/
Proteínas Bacterianas
/
Beta-Lactamasas
/
Elementos Transponibles de ADN
/
Regulación Bacteriana de la Expresión Génica
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Farmacorresistencia Bacteriana Múltiple
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Klebsiella pneumoniae
País/Región como asunto:
Europa
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2016
Tipo del documento:
Article
País de afiliación:
Italia