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APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions.
Kazanov, Marat D; Roberts, Steven A; Polak, Paz; Stamatoyannopoulos, John; Klimczak, Leszek J; Gordenin, Dmitry A; Sunyaev, Shamil R.
Afiliación
  • Kazanov MD; Research and Training Center on Bioinformatics, A.A. Kharkevich Institute for Information Transmission Problems, RAS, Moscow 127051, Russia.
  • Roberts SA; National Institute of Environmental Health Sciences, Durham, NC 27709, USA; School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA.
  • Polak P; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Stamatoyannopoulos J; Departments of Genome Sciences and Medicine, University of Washington, Seattle, WA 98195, USA.
  • Klimczak LJ; National Institute of Environmental Health Sciences, Durham, NC 27709, USA.
  • Gordenin DA; National Institute of Environmental Health Sciences, Durham, NC 27709, USA. Electronic address: gordenin@niehs.nih.gov.
  • Sunyaev SR; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: ssunyaev@rics.bwh.harvard.edu.
Cell Rep ; 13(6): 1103-1109, 2015 Nov 10.
Article en En | MEDLINE | ID: mdl-26527001
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Eucromatina / Citidina Desaminasa / Replicación del ADN / Tasa de Mutación / Neoplasias Pulmonares Límite: Female / Humans Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Eucromatina / Citidina Desaminasa / Replicación del ADN / Tasa de Mutación / Neoplasias Pulmonares Límite: Female / Humans Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Estados Unidos