[Preliminary results from the French study on prenatal repair for fetal myelomeningoceles (the PRIUM study)]. / Résultats préliminaires de l'étude PRIUM : programme de réparation in utero des myéloméningocèles.
J Gynecol Obstet Biol Reprod (Paris)
; 45(7): 738-44, 2016 Sep.
Article
en Fr
| MEDLINE
| ID: mdl-26566108
ABSTRACT
OBJECTIVES:
To present the preliminary results of the PRIUM study, a French pilot study of prenatal repair for myelomeningoceles (MMC). MATERIAL ANDMETHODS:
The fetal surgery for MMC is offered in cases of patients that did not opt for termination of pregnancy.RESULTS:
Thirty-six patients were referred in an 18-month period. Eight patients were not eligible for prenatal repair. Another type of dysraphism was made in 6 cases (one spina-lipoma, 5 cases of limited dorsal myeloschisis). Twenty-two patients were eligible to fetal surgery. A prenatal repair was performed in three cases (14%). Four patients opted for a conventional postnatal treatment. Fifteen patients opted for termination of the pregnancy.CONCLUSION:
The establishment of a prenatal repair of MMC protocol in France was justified. The experience of the first 18months of this study however suggests that only a limited number of couples will choose this procedure after specialized counseling in a reference center.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Meningomielocele
/
Terapias Fetales
/
Enfermedades Fetales
Tipo de estudio:
Guideline
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
País/Región como asunto:
Europa
Idioma:
Fr
Revista:
J Gynecol Obstet Biol Reprod (Paris)
Año:
2016
Tipo del documento:
Article
País de afiliación:
Francia