[Therapeutic applications of closed-loop brain stimulation. Success and expectations]. / Therapeutischer Einsatz von Closed-loop-Hirnstimulation. Erfolge und Erwartungen.
Nervenarzt
; 86(12): 1523-7, 2015 Dec.
Article
en De
| MEDLINE
| ID: mdl-26567042
ABSTRACT
The therapeutic application of brain stimulation is still limited to relatively few indications and small groups of patients due to variable efficacy. Individualization of stimulation parameters by employing a closed-loop system, i.e. synchronization of stimulation with endogenous brain activity with millisecond precision, has the potential to significantly improve the therapeutic efficacy when compared to open-loop systems. In this article the theoretical and experimental results are reviewed including first clinical trials that support the superiority of closed-loop brain stimulation, fundamental aspects in the development of closed loop methods are discussed and clinical studies which could quantify an increase in effectiveness are summarized. A significant increase in the indications for therapeutic applications of closed-loop systems is to be expected in the near future.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estimulación Magnética Transcraneal
/
Neurorretroalimentación
/
Estimulación Transcraneal de Corriente Directa
/
Trastornos Mentales
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
De
Revista:
Nervenarzt
Año:
2015
Tipo del documento:
Article