Limb-Threatening Acute Venous Thromboembolism in a Patient Undergoing Postarrest Therapeutic Hypothermia.
Ther Hypothermia Temp Manag
; 5(4): 228-34, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-26575600
ABSTRACT
Postcardiac arrest patients are at high risk for developing venous thromboembolism (VTE). Current postarrest guidelines do not provide recommendations for prevention or surveillance of VTE and there is little guidance regarding the optimal prophylaxis or treatment of VTE during therapeutic hypothermia (TH). Many patients develop acute liver dysfunction resulting from severe global hypoperfusion during cardiac arrest, compounding concerns for bleeding with the initiation of TH. However, significant VTE may occur following arrest and can contribute to additional morbidity and mortality. The pharmacokinetics of anticoagulation, the routine treatment for VTE, have not been extensively researched or tested under hypothermic conditions. Standard approaches for prevention and treatment have been utilized, such as unfractionated heparin, but their efficacy remains uncertain. This case illustrates the significant imbalance of coagulation in a postcardiac arrest patient undergoing TH.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tromboembolia Venosa
/
Paro Cardíaco
/
Hipotermia Inducida
Tipo de estudio:
Diagnostic_studies
/
Guideline
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Ther Hypothermia Temp Manag
Año:
2015
Tipo del documento:
Article