Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator-Activated Receptor-Î³ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate-Salt Hypertension.

Ketsawatsomkron, Pimonrat; Keen, Henry L; Davis, Deborah R; Lu, Ko-Ting; Stump, Madeliene; De Silva, T Michael; Hilzendeger, Aline M; Grobe, Justin L; Faraci, Frank M; Sigmund, Curt D

Ketsawatsomkron, Pimonrat; Keen, Henry L; Davis, Deborah R; Lu, Ko-Ting; Stump, Madeliene; De Silva, T Michael; Hilzendeger, Aline M; Grobe, Justin L; Faraci, Frank M; Sigmund, Curt D.

Afiliación

Ketsawatsomkron P; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Keen HL; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Davis DR; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Lu KT; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Stump M; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
De Silva TM; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Hilzendeger AM; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Grobe JL; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Faraci FM; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA.
Sigmund CD; From the Department of Pharmacology, Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City; and Iowa City Veterans Affairs Healthcare System, IA. curt-sigmund@uiowa.edu.

Hypertension ; 67(1): 214-22, 2016 Jan.

Article en En | MEDLINE | ID: mdl-26597823

Asunto(s)

ADN/genética; Regulación de la Expresión Génica; Hipertensión/genética; Músculo Liso Vascular/metabolismo; PPAR gamma/genética; Inhibidores Tisulares de Metaloproteinasas/genética; Animales; Presión Sanguínea/fisiología; Acetato de Desoxicorticosterona/toxicidad; Modelos Animales de Enfermedad; Hipertensión/metabolismo; Hipertensión/fisiopatología; Ratones; Ratones Transgénicos; Músculo Liso Vascular/fisiopatología; PPAR gamma/metabolismo; Inhibidores Tisulares de Metaloproteinasas/antagonistas & inhibidores; Vasoconstricción; Inhibidor Tisular de Metaloproteinasa-4

Palabras clave

PPARÎ³; hypertension; smooth muscle; tissue inhibitor of metalloproteinase-4; vascular remodeling

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Regulación de la Expresión Génica / Inhibidores Tisulares de Metaloproteinasas / PPAR gamma / Hipertensión / Músculo Liso Vascular Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Hypertension Año: 2016 Tipo del documento: Article

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