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Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells.
Rushworth, Stuart A; Pillinger, Genevra; Abdul-Aziz, Amina; Piddock, Rachel; Shafat, Manar S; Murray, Megan Y; Zaitseva, Lyubov; Lawes, Matthew J; MacEwan, David J; Bowles, Kristian M.
Afiliación
  • Rushworth SA; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Pillinger G; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Abdul-Aziz A; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Piddock R; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Shafat MS; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Murray MY; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Zaitseva L; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.
  • Lawes MJ; Department of Haematology, Norfolk and Norwich University Hospitals NHS Trust, Norwich, UK.
  • MacEwan DJ; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Bowles KM; Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK; Department of Haematology, Norfolk and Norwich University Hospitals NHS Trust, Norwich, UK. Electronic address: k.bowles@uea.ac.uk.
Lancet Haematol ; 2(5): e204-11, 2015 May.
Article en En | MEDLINE | ID: mdl-26688095
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Proteínas Tirosina Quinasas / Leucemia Mieloide Aguda / Transducción de Señal Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Haematol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Proteínas Tirosina Quinasas / Leucemia Mieloide Aguda / Transducción de Señal Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Haematol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido