Comparative accuracy of supine-only and combined supine-prone myocardial perfusion imaging in men.
J Nucl Cardiol
; 23(6): 1470-1476, 2016 12.
Article
en En
| MEDLINE
| ID: mdl-26719152
ABSTRACT
BACKGROUND:
Combined supine-prone myocardial perfusion imaging (CSP MPI) has been shown to reduce attenuation artifact in comparison to supine-only (SU) MPI in mixed-gender populations with varying risk for coronary artery disease (CAD), often where patients served as their own controls. However, there is limited direct comparison of these imaging strategies in men.METHODS:
934 male patients underwent CSP or SU MPI. Diagnostic certainty of interpretation was compared. Within the cohort, 116 were referred for left heart catheterization (LHC) to assess for CAD. Sensitivity, specificity, and area under the curve (AUC) were compared with additional analysis based on body mass index (BMI).RESULTS:
597 patients completed the SU protocol and 337 patients completed the CSP protocol. Equivocal studies were seen more frequently in the SU group (13%) than in the CSP group (4%, P < .001). At catheterization, the specificity for CSP MPI of 70% was higher than 40% for SU MPI (P = .032). The CSP AUC (0.80 ± 0.06) was significantly larger than SU AUC (0.57 ± 0.05, P = .004). CSP specificity was significantly higher in obese patients.CONCLUSIONS:
CSP MPI increases diagnostic certainty and improves test accuracy for CAD detection in men with CAD risk factors, especially obese patients, compared to SU MPI.Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de la Arteria Coronaria
/
Tomografía Computarizada por Emisión de Fotón Único Sincronizada Cardíaca
/
Imagen de Perfusión Miocárdica
/
Posicionamiento del Paciente
/
Obesidad
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Prevalence_studies
/
Prognostic_studies
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Nucl Cardiol
Asunto de la revista:
CARDIOLOGIA
Año:
2016
Tipo del documento:
Article
País de afiliación:
Estados Unidos