[The Development of Luminescent Nano-probes on Hard X-ray Irradiation].
Yakugaku Zasshi
; 136(1): 17-20, 2016.
Article
en Ja
| MEDLINE
| ID: mdl-26725662
ABSTRACT
X-rays are widely used in imaging applications such as diffraction imaging of crystals and medical imaging. In particular, X-ray computed tomography (CT) is a critical tool for clinical and disease diagnostics. The principle of conventional CT is based on X-ray attenuation caused by photoelectric absorption and scattering. In addition to conventional CT, a number of novel methodologies are presently under development, including state-of-the-art instrument technologies and chemical probes to fulfill diagnosis criteria. Among these novel methodologies, we have utilized hard X-ray-excited optical luminescence (hXEOL) as a new methodology to enhance the contrast of the image. Herein, we explored the possibility of hXEOL via iridium-doped polymer nanoparticles and biomolecule-directed metal clusters and propose it as a potential platform for new X-ray imaging.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diagnóstico por Imagen
/
Sondas Moleculares
/
Tomografía Computarizada por Rayos X
/
Luminiscencia
/
Nanoestructuras
/
Nanopartículas del Metal
/
Imagen Molecular
Tipo de estudio:
Diagnostic_studies
Idioma:
Ja
Revista:
Yakugaku Zasshi
Año:
2016
Tipo del documento:
Article