The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity.

Clement, Cristina C; Becerra, Aniuska; Yin, Liusong; Zolla, Valerio; Huang, Liling; Merlin, Simone; Follenzi, Antonia; Shaffer, Scott A; Stern, Lawrence J; Santambrogio, Laura

Clement, Cristina C; Becerra, Aniuska; Yin, Liusong; Zolla, Valerio; Huang, Liling; Merlin, Simone; Follenzi, Antonia; Shaffer, Scott A; Stern, Lawrence J; Santambrogio, Laura.

Afiliación

Clement CC; From the Departments of Pathology and.
Becerra A; the Departments of Pathology and.
Yin L; the Departments of Pathology and.
Zolla V; From the Departments of Pathology and.
Huang L; From the Departments of Pathology and.
Merlin S; the School of Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Follenzi A; From the Departments of Pathology and; the School of Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Shaffer SA; Biochemistry and Molecular Pharmacology and; the Proteomics and Mass Spectrometry Facility, University of Massachusetts Medical School, Worcester, Massachusetts 01655, and.
Stern LJ; the Departments of Pathology and; Biochemistry and Molecular Pharmacology and.
Santambrogio L; From the Departments of Pathology and; Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461,. Electronic address: laura.santambrogio@einstein.yu.edu.

J Biol Chem ; 291(11): 5576-5595, 2016 Mar 11.

Article en En | MEDLINE | ID: mdl-26740625

Asunto(s)

Células Dendríticas/metabolismo; Antígeno HLA-DR1/metabolismo; Péptidos/metabolismo; Proteoma/metabolismo; Secuencia de Aminoácidos; Animales; Células Cultivadas; Colágeno Tipo II/química; Colágeno Tipo II/metabolismo; Complemento C3/química; Complemento C3/metabolismo; Células Dendríticas/química; Gelsolina/química; Gelsolina/metabolismo; Antígeno HLA-DR1/química; Humanos; Linfa/metabolismo; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; Datos de Secuencia Molecular; Péptidos/química; Unión Proteica; Proteoma/química; Proteómica; Transducción de Señal; Timosina/química; Timosina/metabolismo

Palabras clave

antigen presentation; antigen processing; dendritic cell; immunological tolerance; lymph; major histocompatibility complex (MHC); proteomics; tolerance

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Células Dendríticas / Antígeno HLA-DR1 / Proteoma Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos

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