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Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice.
Krishnamoorthy, Sriram; Liu, Tongyao; Drager, Douglas; Patarroyo-White, Susannah; Chhabra, Ekta Seth; Peters, Robert; Josephson, Neil; Lillicrap, David; Blumberg, Richard S; Pierce, Glenn F; Jiang, Haiyan.
Afiliación
  • Krishnamoorthy S; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States. Electronic address: sriram.krishnamoorthy@biogen.com.
  • Liu T; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States.
  • Drager D; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States.
  • Patarroyo-White S; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States.
  • Chhabra ES; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States.
  • Peters R; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States.
  • Josephson N; Division of Hematology, University of Washington School of Medicine, Puget Sound Blood Center, Seattle, WA 98104, United States.
  • Lillicrap D; Department of Pathology and Molecular Medicine, Queen's University, Kingston, Canada.
  • Blumberg RS; Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
  • Pierce GF; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States.
  • Jiang H; Hematology Research, Biogen, 115 Broadway, Cambridge, MA 02142, United States. Electronic address: haiyan.jiang.b@gmail.com.
Cell Immunol ; 301: 30-9, 2016 Mar.
Article en En | MEDLINE | ID: mdl-26775174
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Factor VIII / Fragmentos Fc de Inmunoglobulinas / Hemofilia A / Tolerancia Inmunológica Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cell Immunol Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Factor VIII / Fragmentos Fc de Inmunoglobulinas / Hemofilia A / Tolerancia Inmunológica Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cell Immunol Año: 2016 Tipo del documento: Article Pais de publicación: Países Bajos